Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 9/20 | 0.49 |
| ▸ | ATP4B | P51164 | 9/20 | 0.49 |
| ▸ | HRH2 | P25021 | 3/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645323 | 1.00 | ATP4A (0.49) | ATP4AATP4BHRH2HRH4ROCK2 | |
| SCHEMBL8643845 | 0.94 | ATP4A (0.48) | ATP4AATP4BHRH2HRH4ROCK2 | |
| SCHEMBL8643846 | 0.94 | ATP4A (0.48) | ATP4AATP4BHRH2HRH4ROCK2 | |
| Hydrochloric Acid SCHEMBL8648326 | 0.93 | ATP4A (0.49) | ATP4AATP4BHRH2HRH4ROCK2 | |
| Hydrochloric Acid SCHEMBL8648324 | 0.93 | ATP4A (0.49) | ATP4AATP4BHRH2HRH4ROCK2 | |
| Hydrochloric Acid SCHEMBL8651698 | 0.93 | ATP4A (0.49) | ATP4AATP4BHRH2HRH4ROCK2 | |
| Hydrochloric Acid SCHEMBL8651701 | 0.93 | ATP4A (0.49) | ATP4AATP4BHRH2HRH4ROCK2 | |
| SCHEMBL8646457 | 0.92 | ATP4A (0.47) | ATP4AATP4BHRH2HRH4ROCK2 | |
| SCHEMBL8646465 | 0.92 | ATP4A (0.47) | ATP4AATP4BHRH2HRH4ROCK2 | |
| Hydrochloric Acid SCHEMBL8646336 | 0.91 | ATP4A (0.48) | ATP4AATP4BHRH2HRH4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545376-B1 | Guanidino thiazoles and their use as H2-receptor antagonist | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5532258-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0545376-A1 | Guanidino thiazoles and their use as H2-receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |