SCHEMBL8645360

SCHEMBL8645360

CCC(CNc1ccccc1)Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.44
MAPK1 P28482 6/20 0.44
SMN1; SMN2 Q16637 6/20 0.44
NPSR1 Q6W5P4 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
HTT P42858 4/20 0.44
UBE2N P61088 2/20 0.44
MITF O75030 1/20 0.44
ALDH1A1 P00352 1/20 0.42
RAD52 P43351 2/20 0.40
STAT3 P40763 1/20 0.40
RCE1 Q9Y256 1/20 0.40
GLA P06280 1/20 0.39
RAB9A P51151 3/20 0.38
APAF1 O14727 1/20 0.38
HSP90AA1 P07900 1/20 0.38
NOD2 Q9HC29 1/20 0.38
NPC1 O15118 2/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10597608 0.84 MAPK1 (0.39) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL9497650 0.84 MAPK1 (0.38) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL8758159 0.83 MAPK1 (0.39) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL9490784 0.82 MAPK1 (0.43) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL10891798 0.79 MAPK1 (0.50) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL10396118 0.79 MAPK1 (0.47) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL11689458 0.79 MAPK1 (0.47) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL14564633 0.77 KMT2A (0.46) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL10707116 0.76 MAPK1 (0.37) MAPTMAPK1SMN1; SMN2NPSR1MEN1
SCHEMBL5489761 0.74 MAPK1 (0.50) MAPTMAPK1SMN1; SMN2NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0464612-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
US-5350666-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1994-09-27 US disclosed
EP-0464612-A1 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-01-08 EP disclosed