SCHEMBL9490784

SCHEMBL9490784

CCC(CNc1ccc(NNC(C)=O)cc1)Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.43
NPSR1 Q6W5P4 5/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 4/20 0.34
HTT P42858 3/20 0.34
UBE2N P61088 2/20 0.34
GLA P06280 1/20 0.34
MITF O75030 1/20 0.34
RAD52 P43351 2/20 0.34
STAT3 P40763 1/20 0.34
RCE1 Q9Y256 1/20 0.34
ACACB O00763 1/20 0.34
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 2/20 0.32
APAF1 O14727 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8758159 0.84 MAPK1 (0.39) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10612948 0.84 NPC1 (0.36) SMN1; SMN2KMT2AALDH1A1MAPTHTT
SCHEMBL9166429 0.83 NPSR1 (0.43) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8645360 0.82 MAPT (0.44) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10904071 0.81 MAPK1 (0.43) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10994495 0.81 SMN1; SMN2 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10779945 0.77 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10779937 0.77 MEN1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9497650 0.77 MAPK1 (0.38) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10891798 0.75 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0224214-B1 LIGHT-SENSITIVE MICROCAPSULE CONTAINING POLYMERIZABLE COMPOUND AND SILVER HALIDE, AND LIGHT-SENSITIVE MATERIAL EMPLOYING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1993-01-27 EP disclosed
US-5073472-A Containing microcapsules differing in exposure sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1991-12-17 US disclosed
EP-0265954-B1 LIGHT-SENSITIVE MATERIAL CONTAINING SILVER HALIDE, REDUCING AGENT AND POLYMERIZABLE COMPOUND Fuji Photo Film Co., Ltd. (JP) 1991-09-25 EP disclosed
US-5030543-A Multilayer with colored surface FUJI PHOTO FILM CO., LTD. (JP) 1991-07-09 US disclosed
US-4963460-A SILVER HALIDE, REDUCING AGENT, AND ETHYLENIC UNSATURATED POLYMERIZABLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-10-16 US disclosed
EP-0254181-A2 Image-forming method employing light-sensitive material containing silver halide, reducing agent and polymerizable compound FUJI PHOTO FILM CO., LTD. (JP) 1988-01-27 EP disclosed