Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645595 | 1.00 | KMT2A (0.58) | KMT2AAKR1C3MEN1ALDH1A1CYP1A1 | |
| SCHEMBL8648334 | 0.88 | KMT2A (0.58) | KMT2AMEN1ALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL8648329 | 0.88 | KMT2A (0.58) | KMT2AMEN1ALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL24055175 | 0.86 | CYP1A1 (0.62) | KMT2AAKR1C3MEN1ALDH1A1CYP1A1 | |
| SCHEMBL30211768 | 0.86 | CYP1A1 (0.62) | KMT2AAKR1C3MEN1ALDH1A1CYP1A1 | |
| SCHEMBL8645501 | 0.86 | ALDH1A1 (0.74) | KMT2AMEN1ALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL8645503 | 0.86 | ALDH1A1 (0.74) | KMT2AMEN1ALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL4365603 | 0.84 | ALDH1A1 (0.70) | KMT2AAKR1C3MEN1ALDH1A1CYP1A2 | |
| SCHEMBL4365600 | 0.84 | ALDH1A1 (0.70) | KMT2AAKR1C3MEN1ALDH1A1CYP1A2 | |
| SCHEMBL13950671 | 0.84 | ALDH1A1 (0.70) | KMT2AAKR1C3MEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861831-A1 | HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |