Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645814 | 1.00 | DPP7 (0.41) | DPP7EPORF2ADRA2CTP53 | |
| SCHEMBL8710584 | 0.83 | CDK5 (0.40) | DPP7EPORF2 | |
| SCHEMBL8664225 | 0.81 | EPOR (0.51) | EPORMMP2CPB2ITGB3ITGA2B | |
| SCHEMBL7321837 | 0.76 | F2 (0.50) | DPP7EPORF2ADRA2CMMP2 | |
| SCHEMBL9716623 | 0.76 | F2 (0.50) | DPP7EPORF2ADRA2CMMP2 | |
| SCHEMBL1387992 | 0.76 | F2 (0.50) | DPP7EPORF2ADRA2CMMP2 | |
| SCHEMBL29911663 | 0.74 | F2 (0.42) | DPP7EPORF2ADRA2CMMP2 | |
| SCHEMBL26664964 | 0.74 | F2 (0.42) | DPP7EPORF2ADRA2CMMP2 | |
| SCHEMBL7219138 | 0.73 | EPOR (0.38) | DPP7EPORF2TSHRTDP1 | |
| SCHEMBL1387641 | 0.73 | ADRA2C (0.54) | DPP7EPORF2ADRA2CTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861260-A1 | IMPROVED METHOD AND AGENTS FOR INHIBITING PROTEIN AGING | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997018223-A1 | IMPROVED METHOD AND AGENTS FOR INHIBITING PROTEIN AGING | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1997-05-22 | — | — | WO | disclosed |