SCHEMBL8645860

SCHEMBL8645860

C=CC(O)NCCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
BLM P54132 1/20 0.42
SLC6A3 Q01959 1/20 0.42
MEN1 O00255 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
ABCC4 O15439 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ECE1 P42892 4/20 0.33
TET2 Q6N021 3/20 0.33
LMNA P02545 3/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4192117 0.78
SCHEMBL526331 0.77
SCHEMBL29953253 0.77 SLC6A2 (0.41) SLC6A2SLC6A4BLMSLC6A3MEN1
Acetic Acid SCHEMBL21616797 0.74 GGT1 (0.36) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL2781177 0.72 TSHR (0.40) TSHR
SCHEMBL3087186 0.72 FOLH1 (0.37) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL149333 0.70 TET2 (0.42) ECE1TET2LMNAKDM4AKDM4C
SCHEMBL8369782 0.70
SCHEMBL4782152 0.70
SCHEMBL17210141 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585745-B1 Direct positive silver halide photographic material and method for forming high contrast positive image using the same DAINIPPON INK & CHEMICALS (JP) 1999-03-24 EP disclosed
US-5362621-A Compound containing pyridine and pyridinium nucleus, reductone developer DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-11-08 US disclosed
EP-0585745-A2 Direct positive silver halide photographic material and method for forming high contrast positive image using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-03-09 EP disclosed