Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | FABP3 | P05413 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Behenic Acid SCHEMBL10478093 | 1.00 | NFKB1 (0.59) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Palmitic Acid SCHEMBL27509600 | 1.00 | NFKB1 (0.59) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Stearic Acid SCHEMBL28265891 | 0.98 | NFKB1 (0.58) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Stearic Acid SCHEMBL6911083 | 0.96 | NFKB1 (0.65) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Stearic Acid SCHEMBL29874636 | 0.96 | NFKB1 (0.59) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Palmitic Acid SCHEMBL11280216 | 0.96 | NFKB1 (0.65) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Dodecanoate SCHEMBL11277766 | 0.96 | NFKB1 (0.65) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Stearic Acid SCHEMBL1502513 | 0.96 | NFKB1 (0.59) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Stearic Acid SCHEMBL7457395 | 0.96 | NFKB1 (0.59) | NFKB1GPR84FABP3KDM4EDUSP3 | |
| Octanoic Acid SCHEMBL17395727 | 0.96 | NFKB1 (0.65) | NFKB1GPR84FABP3KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101081902-B | Orientation reinforced polymer material and its uses | ATOFINC RES | 2012-07-18 | — | — | CN | disclosed |
| US-5719213-A | Auxiliary agent for processing plastics, a method for preparing the agent and a method for producing unsaturated polyester resins characterized by supressed vaporization of the monomer component | INSTYTUT CHEMII PRZEMYSLOWEI (PL) | 1998-02-17 | — | — | US | disclosed |
| EP-0691372-A2 | Lubricants for thermoplastics and compositions containing them | COMIEL S.p.A. (IT) | 1996-01-10 | — | — | EP | disclosed |