Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 12/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.32 |
| ▸ | MVD | P53602 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483954 | 0.83 | CA12 (0.40) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL1075365 | 0.83 | CA12 (0.40) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL8641429 | 0.81 | CA12 (0.39) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL1075367 | 0.77 | CA12 (0.38) | CA12CA1CA2CA9CHRM2 | |
| SCHEMBL22733778 | 0.76 | LPAR3 (0.48) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL4333965 | 0.76 | USP2 (0.42) | LPAR3LPAR2LPAR1MVD | |
| SCHEMBL14047362 | 0.75 | CHRM2 (0.38) | CA12CA1CA2CA9CHRM2 | |
| SCHEMBL1642999 | 0.75 | LPAR3 (0.46) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL28666575 | 0.75 | LPAR3 (0.42) | LPAR3LPAR2LPAR1CHRM2CHRM1 | |
| SCHEMBL7132612 | 0.73 | CHRM2 (0.41) | LPAR3LPAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195578-B | Use of phosphorothioate derivatives as skin depigmenting agents | 塞恩提斯有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-122031506-A | Chiral control | 波涛生命科学有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| EP-4219516-A2 | CHIRAL CONTROL | Wave Life Sciences Ltd. (SG) | 2023-08-02 | — | — | EP | disclosed |
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| EP-2872147-B1 | METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES | WAVE LIFE SCIENCES LTD (SG) | 2022-12-21 | — | — | EP | disclosed |
| US-20210130821-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2021-05-06 | — | — | US | disclosed |
| CN-112007045-A | Chiral control | 波涛生命科学有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-104661664-B | Chiral control | 波涛生命科学有限公司 | 2020-07-03 | — | — | CN | disclosed |
| US-10590413-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2020-03-17 | — | — | US | disclosed |
| US-9982257-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2018-05-29 | — | — | US | disclosed |
| US-9885037-B2 | — | — | 2018-02-06 | — | — | US | disclosed |
| US-20170275621-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2017-09-28 | — | — | US | disclosed |
| US-20150211006-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2015-07-30 | — | — | US | disclosed |
| EP-2872147-A2 | CHIRAL CONTROL | Wave Life Sciences Pte. Ltd. (SG) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014012081-A2 | CHIRAL CONTROL | ONTORII, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130821-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | LPAR3 293/4885LPAR2 914/4885CA12 876/4885 |
| US-20170275621-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | LPAR3 293/4885LPAR2 914/4885CA12 876/4885 |
| US-20240229026-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | LPAR3 293/4885LPAR2 914/4885CA12 876/4885 |
| US-20150211006-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | LPAR3 293/4885LPAR2 914/4885CA12 876/4885 |
| US-11643657-B2 | Chiral control | RNGTT, POLI, NSUN3 | LPAR3 293/4885LPAR2 914/4885CA12 876/4885 |
| US-10590413-B2 | Chiral control | RNGTT, POLI, NSUN3 | LPAR3 293/4885LPAR2 914/4885CA12 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.