SCHEMBL8645936

SCHEMBL8645936

CCN1CCOCC1.On1nnc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.58
MAPK1 P28482 1/20 0.58
ATM Q13315 1/20 0.58
CYP2D6 P10635 1/20 0.58
SLC9A1 P19634 3/20 0.46
LMNA P02545 2/20 0.45
HSD17B10 Q99714 2/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HPGD P15428 3/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 1/20 0.41
TDP2 O95551 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4719815 0.84 POLB (0.64) POLBMAPK1ATMCYP2D6SLC9A1
Tetrahydrofuran SCHEMBL28309768 0.81 MAPK1 (0.72) POLBMAPK1ATMCYP2D6SLC9A1
Alcohol SCHEMBL9949018 0.77 POLB (0.78) POLBMAPK1ATMCYP2D6SLC9A1
SCHEMBL1012471 0.76 POLB (1.00) POLBMAPK1ATMCYP2D6SLC9A1
SCHEMBL3672275 0.76 POLB (1.00) POLBMAPK1ATMCYP2D6SLC9A1
SCHEMBL184 0.76 POLB (1.00) POLBMAPK1ATMCYP2D6SLC9A1
Phosphine SCHEMBL23702726 0.75 POLB (0.95) POLBMAPK1ATMCYP2D6SLC9A1
SCHEMBL6827564 0.75 POLB (0.95) POLBMAPK1ATMCYP2D6SLC9A1
Water SCHEMBL12099335 0.75 POLB (0.95) POLBMAPK1ATMCYP2D6SLC9A1
SCHEMBL875034 0.75 POLB (0.95) POLBMAPK1ATMCYP2D6SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770622-A APPLYING TO WOOD, LEATHER, POLYMERS, PAPER, WATER BAYER AKTIENGESELLSCHAFT (DE) 1998-06-23 US disclosed
US-5739160-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-14 US disclosed
US-5631291-A BACTERICIDES AND FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-20 US disclosed