SCHEMBL8646152

SCHEMBL8646152

CCCCCC(C)(C)c1ccc(OC)c(S(=O)(=O)Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 18/20 0.53
CNR1 P21554 12/20 0.53
POLB P06746 1/20 0.43
GPR55 Q9Y2T6 1/20 0.40
TRPV4 Q9HBA0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7651314 0.87 CNR2 (0.46) CNR2CNR1
SCHEMBL10642296 0.84 TRPV4 (0.45) TRPV4
SCHEMBL10511426 0.83 CNR2 (0.41) CNR2CNR1
SCHEMBL8646151 0.81 TRPV4 (0.45) POLBTRPV4
SCHEMBL8643908 0.78 CNR2 (0.45) CNR2CNR1
SCHEMBL4944543 0.78 SMN1; SMN2 (0.56) TRPV4
SCHEMBL10568858 0.78 FLT3 (0.46) CNR2CNR1POLB
SCHEMBL6152036 0.77 CNR2 (0.57) CNR2CNR1
SCHEMBL3978727 0.77 FLT3 (0.46) POLB
SCHEMBL7651309 0.76 ESR1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545491-B1 Photographic silver halide colour materials KODAK LTD (GB) 1998-10-14 EP disclosed
EP-0565165-B1 Photographic silver halide colour materials KODAK LTD (GB) 1998-09-02 EP disclosed
US-5415981-A Sulfohydrazide developer, heteroarylacetonitrile color coupler EASTMAN KODAK COMPANY (US) 1995-05-16 US disclosed
US-5284739-A Devloper and coupler present in drops of a high-boiling solvent; water pollution control EASTMAN KODAK COMPANY (US) 1994-02-08 US disclosed
EP-0565165-A1 Photographic silver halide colour materials KODAK LIMITED (GB) 1993-10-13 EP disclosed
EP-0545491-A1 Photographic silver halide colour materials KODAK LIMITED (GB) 1993-06-09 EP disclosed