Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879609 | 0.89 | GAA (0.53) | GAAQPCTSMN1; SMN2NPC1MEN1 | |
| SCHEMBL7868525 | 0.79 | QPCT (0.51) | GAAQPCTSMN1; SMN2NPC1MEN1 | |
| SCHEMBL8648272 | 0.78 | GAA (0.54) | GAASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL7875125 | 0.78 | KMT2A (0.43) | GAAQPCTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL9021076 | 0.77 | GAA (0.41) | GAAQPCTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8226157 | 0.75 | NPC1 (0.57) | SMN1; SMN2NPC1KMT2APOLBCYP1A2 | |
| SCHEMBL8646520 | 0.72 | SMN1; SMN2 (0.50) | GAAQPCTSMN1; SMN2NPC1MEN1 | |
| SCHEMBL8646206 | 0.72 | GAA (0.42) | GAAQPCTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL13762099 | 0.72 | MEN1 (0.78) | GAASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL21098369 | 0.69 | SMN1; SMN2 (0.89) | GAASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |