Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650321 | 0.92 | TP53 (0.32) | CYP2C9MAPT | |
| SCHEMBL8650738 | 0.86 | — | — | |
| SCHEMBL8648095 | 0.81 | CYP2C9 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8648097 | 0.81 | CYP2C9 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9013074 | 0.80 | CYP2C9 (0.42) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9013078 | 0.80 | CYP2C9 (0.42) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9067647 | 0.79 | CYP2C9 (0.34) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9067651 | 0.79 | CYP2C9 (0.34) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL18215465 | 0.78 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL18310500 | 0.77 | CYP2C9 (0.38) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800734-A | 1-fluorocyclohexene-difluorophenyl derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |
| EP-0736513-A1 | 1-Fluorcyclohexene-difluorphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-10-09 | — | — | EP | disclosed |