Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26230949 | 0.86 | FLT4 (0.49) | FLT4KDREGFRTDP1HTT | |
| SCHEMBL20008181 | 0.85 | ADORA2A (0.58) | FLT4KDREGFRTDP1HTT | |
| SCHEMBL3457849 | 0.85 | EGFR (0.54) | FLT4KDREGFRTDP1HTT | |
| SCHEMBL6690200 | 0.85 | TDP1 (0.49) | TDP1HTTMKNK1ALDH1A1TSHR | |
| SCHEMBL27967584 | 0.83 | TMIGD3 (0.65) | TDP1HTTTSHRPDE4APDE4B | |
| SCHEMBL13672568 | 0.83 | TDP1 (0.44) | FLT4KDREGFRTDP1MKNK1 | |
| SCHEMBL27681520 | 0.80 | HTT (0.45) | FLT4KDREGFRHTTPDE4A | |
| SCHEMBL9702446 | 0.80 | CYP1A2 (0.51) | FLT4KDREGFRHTTPDE4A | |
| SCHEMBL9230643 | 0.80 | HDAC6 (0.58) | FLT4KDRALDH1A1TMIGD3HDAC1 | |
| SCHEMBL7263226 | 0.79 | ADORA2A (0.52) | FLT4KDREGFRTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863150-A1 | A method for the preparation of nucleic acid binding compound | BOEHRINGER MANNHEIM GMBH (DE) | 1998-09-09 | — | — | EP | disclosed |