Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748343 | 0.91 | HDAC1 (0.58) | HDAC6HDAC1BRD4FLT4KDR | |
| SCHEMBL21011277 | 0.83 | BRD4 (0.56) | HDAC6HDAC1BRD4CDK5CDK5R1 | |
| SCHEMBL7872974 | 0.81 | HDAC1 (0.47) | HDAC6HDAC1FLT4KDRNSD3 | |
| SCHEMBL8646398 | 0.80 | FLT4 (0.50) | HDAC1FLT4KDRRAB9AALDH1A1 | |
| SCHEMBL26230949 | 0.79 | FLT4 (0.49) | HDAC6HDAC1FLT4KDRTMIGD3 | |
| SCHEMBL14192925 | 0.78 | HDAC1 (0.48) | HDAC6HDAC1TMIGD3 | |
| SCHEMBL3254930 | 0.77 | RET (0.55) | BRD4KDRF2DEGS1NPC1 | |
| SCHEMBL3457849 | 0.77 | EGFR (0.54) | HDAC1BRD4FLT4KDRNPC1 | |
| SCHEMBL6046940 | 0.76 | HDAC1 (0.43) | HDAC6HDAC1BRD4FLT4KDR | |
| SCHEMBL14192930 | 0.76 | HDAC6 (0.47) | HDAC6HDAC1FLT4KDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672661-A1 | Substituted N-ethyl-glycinderivatives for the preparation of PNA and PNA-/DNA hybrides | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |