Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 6/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27358260 | 0.78 | HTT (0.39) | HTTBPTFMTNR1AMTNR1BGLO1 | |
| SCHEMBL25310969 | 0.78 | HTR2C (0.49) | HTTHTR6HTR2C | |
| SCHEMBL7798188 | 0.76 | HTR2C (0.54) | CYP19A1BPTFHTR6HTR2C | |
| SCHEMBL5428812 | 0.74 | HTT (0.60) | HTTCYP1A2HTR2C | |
| Hydrochloric Acid SCHEMBL8031634 | 0.74 | HTR2C (0.52) | CYP19A1BPTFHTR6HTR2C | |
| SCHEMBL25311698 | 0.74 | HTR2A (0.55) | HTTHTR2BCYP1A2CYP2C9MTNR1A | |
| SCHEMBL8447037 | 0.72 | HTR1D (0.39) | CYP19A1BPTFCYP1A2CYP2C9HTR2C | |
| SCHEMBL24669584 | 0.71 | EPHX2 (0.37) | HTTMTNR1AMTNR1B | |
| SCHEMBL16836727 | 0.71 | MCL1 (0.40) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL25309043 | 0.70 | HTR2C (0.49) | HTTMTNR1AMTNR1BHTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | disclosed |