Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR1D | P28221 | 9/20 | 0.45 |
| ▸ | BPTF | Q12830 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8031634 | 0.99 | HTR2C (0.52) | HTR2CHTR2AHTR1DBPTFHTR6 | |
| SCHEMBL7804940 | 0.89 | HTR2C (0.57) | HTR2CHTR2AHTR1DHTR6NOS3 | |
| Hydrochloric Acid SCHEMBL8035287 | 0.88 | HTR2C (0.56) | HTR2CHTR2AHTR1DHTR6NOS3 | |
| SCHEMBL8447037 | 0.86 | HTR1D (0.39) | HTR2CHTR2AHTR1DBPTFHTR1B | |
| SCHEMBL7804917 | 0.77 | MCHR1 (0.50) | HTR2CHTR2AHTR1DHTR1B | |
| SCHEMBL16939364 | 0.76 | HTR2C (0.63) | HTR2CHTR2AHTR1DBPTFHTR6 | |
| Hydrochloric Acid SCHEMBL8035365 | 0.76 | MCHR1 (0.49) | HTR2CHTR2AHTR1DHTR1B | |
| SCHEMBL8647472 | 0.76 | CYP19A1 (0.35) | HTR2CBPTFHTR6CYP19A1 | |
| SCHEMBL23956081 | 0.75 | HTR2A (0.69) | HTR2CHTR2AHTR1DBPTFHTR6 | |
| SCHEMBL6597437 | 0.75 | HTR2C (0.61) | HTR2CHTR2AHTR1DBPTFHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |