SCHEMBL8647604

SCHEMBL8647604

C=Cc1ccccc1C(C)(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TSHR P16473 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX12 P18054 1/20 0.39
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 3/20 0.33
CA2 P00918 1/20 0.33
NFKB1 P19838 1/20 0.32
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HTT P42858 1/20 0.31
LMNA P02545 1/20 0.31
RIPK1 Q13546 1/20 0.31
RAB9A P51151 1/20 0.30
ACHE P22303 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2948538 0.87 ALDH1A1 (0.41) ALDH1A1TSHRTDP1ALOX12MEN1
SCHEMBL27805 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTDP1ALOX12MEN1
SCHEMBL29801228 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTDP1ALOX12MEN1
SCHEMBL7141124 0.80 ALDH1A1 (0.43) ALDH1A1TSHRTDP1ALOX12CA2
Benzene SCHEMBL11667348 0.80 ALDH1A1 (0.48) ALDH1A1TSHRTDP1ALOX12MAPT
SCHEMBL20481716 0.79 ALDH1A1 (0.35) ALDH1A1TSHRTDP1ALOX12MAPT
SCHEMBL3473343 0.78 ALDH1A1 (0.41) ALDH1A1TSHRTDP1ALOX12GRIN2D
Butadiene SCHEMBL7155722 0.78 ALDH1A1 (0.46) ALDH1A1TSHRTDP1ALOX12CA2
Hydrochloric Acid SCHEMBL9567693 0.77 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12GRIN2D
SCHEMBL31322074 0.76 TRPV1 (0.37) ALDH1A1TSHRTDP1ALOX12MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0647160-B1 ION EXCHANGE RESIN UNIV MONASH (AU) 1998-09-02 EP claimed