SCHEMBL8647708

SCHEMBL8647708

CC(=O)C(C(C)=O)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
ALOX15 P16050 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.33
OR51E2 Q9H255 1/20 0.33
CRBN Q96SW2 1/20 0.33
ACHE P22303 1/20 0.31
TSHR P16473 1/20 0.31
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9542105 0.93 LMNA (0.47) LMNAALOX15BLMPMP22TDP1
SCHEMBL1588902 0.76 LMNA (0.46) LMNAALOX15BLMPMP22TDP1
SCHEMBL233035 0.76 LMNA (0.46) LMNAALOX15BLMPMP22TDP1
SCHEMBL29289882 0.73 TDP1 (0.47) LMNAALOX15BLMPMP22TDP1
SCHEMBL3464595 0.72 LMNA (0.42) LMNAALOX15BLMPMP22TDP1
SCHEMBL9140583 0.72 LMNA (0.42) LMNAALOX15BLMPMP22TDP1
SCHEMBL3519317 0.72 LMNA (0.42) LMNAALOX15BLMPMP22TDP1
SCHEMBL4347148 0.72 LMNA (0.42) LMNAALOX15BLMPMP22TDP1
SCHEMBL30874330 0.72 LMNA (0.42) LMNAALOX15BLMPMP22TDP1
SCHEMBL1005354 0.72 LMNA (0.42) LMNAALOX15BLMPMP22TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503587-B1 Silver halide colour photographic material FUJI PHOTO FILM CO LTD (JP) 1998-06-24 EP claimed
JP-3269068-A None JP disclosed
CN-121779284-A Diacetylacetarylamine surface modifier, self-dispersion color paste and preparation method 沈阳化工研究院有限公司 2026-04-03 CN disclosed
CN-118593485-B Isoxazoline complexes and compositions thereof M·法伯 2025-04-22 CN disclosed
EP-4504214-A1 NOVEL ISOXAZOLINE COMPLEXES AND COMPOSITIONS THEREOF Smartek International Inc. (US) 2025-02-12 EP disclosed
WO-2024232970-A1 NOVEL ISOXAZOLINE COMPLEXES AND COMPOSITIONS THEREOF SMARTEK INTERNATIONAL INC (US) 2024-11-14 WO disclosed
US-20240366572-A1 ISOXAZOLINE COMPLEXES AND COMPOSITIONS THEREOF FARBER MICHAEL (US) 2024-11-07 US disclosed
CN-118593485-A Isoxazoline complexes and compositions thereof M·法伯 2024-09-06 CN disclosed
US-11903962-B1 Isoxazoline complexes and compositions thereof FARBER MICHAEL (US) 2024-02-20 US disclosed
CN-112469763-B High temperature and aging resistant polyglycolide copolymers and compositions thereof 上海浦景化工技术股份有限公司 2023-11-24 CN disclosed
WO-2015158592-A1 METHODS FOR MANUFACTURING PRINTED TEXTILES AGFA GRAPHICS NV (BE) 2015-10-22 WO disclosed
EP-2933374-A1 Methods for manufacturing printed textiles AGFA GRAPHICS NV (BE) 2015-10-21 EP disclosed
US-5763408-A TUMOR METASTASIS INHIBITORS FUJI PHOTO FILM CO., LTD. (JP) 1998-06-09 US disclosed
US-5559104-A Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use FIDIA S.P.A. (IT) 1996-09-24 US disclosed
EP-0644181-B1 AMINO ACID DERIVATIVE AND USE THEREOF FUJI PHOTO FILM CO LTD (JP) 1996-09-04 EP disclosed
EP-0644181-A1 AMINO ACID DERIVATIVE AND USE THEREOF FUJI PHOTO FILM CO., LTD. (JP) 1995-03-22 EP disclosed
JP-H03269068-A COLORING COMPOSITION FOR IMAGE RECORDING DAINICHISEIKA COLOR & CHEM MFG CO LTD 1991-11-29 JP disclosed
US-4460760-A ADHESIVES OKURA KOGYO KABUSHIKI KAISHA (JP) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366572-A1 ISOXAZOLINE COMPLEXES AND COMPOSITIONS THEREOF CCDC47, CAT, CTTN LMNA 3653/4885ALOX15 4281/4885BLM 3889/4885
US-11903962-B1 Isoxazoline complexes and compositions thereof GRIN2D, PPID, CCDC47 LMNA 2240/4885ALOX15 3624/4885BLM 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.