⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268808 | 0.80 | — | — | |
| SCHEMBL1532338 | 0.67 | MEN1 (0.30) | — | |
| SCHEMBL11419077 | 0.65 | — | — | |
| SCHEMBL6340847 | 0.65 | — | — | |
| SCHEMBL3267702 | 0.63 | THRB (0.36) | — | |
| SCHEMBL8665222 | 0.63 | CA1 (0.31) | — | |
| SCHEMBL3945256 | 0.63 | — | — | |
| SCHEMBL22551770 | 0.63 | — | — | |
| SCHEMBL27931957 | 0.63 | — | — | |
| SCHEMBL4596520 | 0.63 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682649-B1 | DEUTERATED SEVOFLURANE AS AN INHALATIONAL ANESTHETIC | UNIV IOWA RES FOUND (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5789450-A | Deuterated sevoflurane as an inhalational anesthetic | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-08-04 | — | — | US | disclosed |
| US-5492111-A | PASSING EXHALED GASES THROUGH A COOLED CARBON DIOXIDE SCRUBBER | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0682649-A1 | DEUTERATED SEVOFLURANE AS AN INHALATIONAL ANESTHETIC | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5391579-A | A gaseous mixture of fluorodideuteromethyl-1,1,1,3,3,3-hexafluoro-2-propyl ether and oxygen as sedate inhalants | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1995-02-21 | — | — | US | disclosed |
| WO-1994017016-A1 | DEUTERATED SEVOFLURANE AS AN INHALATIONAL ANESTHETIC | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1994-08-04 | — | — | WO | disclosed |