Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15184811 | 1.00 | PIK3CD (0.45) | PIK3CDMEN1KMT2APIK3R2PTPN1 | |
| SCHEMBL864903 | 0.86 | PIK3CD (0.41) | PIK3CDMEN1KMT2APIK3R2NR4A2 | |
| SCHEMBL864902 | 0.86 | PIK3CD (0.41) | PIK3CDMEN1KMT2APIK3R2NR4A2 | |
| SCHEMBL15184786 | 0.85 | PIK3CD (0.49) | PIK3CDPTPN1SOS1KRAS | |
| SCHEMBL863392 | 0.84 | PIK3CD (0.42) | PIK3CDMEN1KMT2APIK3R2SOS1 | |
| SCHEMBL863393 | 0.84 | PIK3CD (0.42) | PIK3CDMEN1KMT2APIK3R2SOS1 | |
| SCHEMBL864067 | 0.83 | PIK3CD (0.39) | PIK3CDMEN1KMT2APIK3R2 | |
| SCHEMBL864066 | 0.83 | PIK3CD (0.39) | PIK3CDMEN1KMT2APIK3R2 | |
| SCHEMBL864696 | 0.79 | PIM1 (0.39) | PIK3CDMEN1KMT2APIK3R2 | |
| SCHEMBL864695 | 0.79 | PIM1 (0.39) | PIK3CDMEN1KMT2APIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396315-B1 | QUINOLINE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-08-31 | — | — | EP | disclosed |
| US-20120077815-A1 | Fused Pyridine And Pyrazine Derivatives As Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077815-A1 | Fused Pyridine And Pyrazine Derivatives As Kinase Inhibitors | PDPK1, PDXK, PIK3CA | PIK3CD 14/4885MEN1 3086/4885KMT2A 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.