Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648284 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL8647892 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL7291497 | 0.82 | KMT2A (0.51) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL8650351 | 0.79 | KMT2A (0.52) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL8647528 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL8647737 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL8650373 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL8642886 | 0.76 | ITGB3 (0.41) | SMN1; SMN2KMT2AHRH3HTTMEN1 | |
| SCHEMBL8644505 | 0.76 | ITGB3 (0.38) | SMN1; SMN2KMT2AHTT | |
| SCHEMBL8646519 | 0.73 | KMT2A (0.46) | SMN1; SMN2KMT2AHRH3HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |