Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109869 | 0.70 | — | — | |
| SCHEMBL5508863 | 0.68 | NISCH (0.50) | ALDH1A1SMN1; SMN2KDR | |
| SCHEMBL6474210 | 0.68 | HIPK2 (0.43) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL114028 | 0.67 | HIPK2 (0.41) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10402412 | 0.64 | HIPK2 (0.40) | HIPK2 | |
| SCHEMBL10586793 | 0.63 | CDC7 (0.47) | ALDH1A1 | |
| SCHEMBL17844059 | 0.63 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KDRTLR8 | |
| SCHEMBL5387033 | 0.63 | MKNK1 (0.46) | ALDH1A1SMN1; SMN2KDRTLR8 | |
| SCHEMBL1407881 | 0.63 | CYP3A4 (0.46) | SMN1; SMN2 | |
| SCHEMBL6087209 | 0.62 | HIPK2 (0.34) | HIPK2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707967-A | AN AMINO ACID FOR PAIN DUE TO ASPARTAME OR MONOSODIUM GLUTAMATE | VANMOOR ARTHUR (US) | 1998-01-13 | — | — | US | disclosed |
| US-5708029-A | HYPOTENSIVE AGENTS, AMINO ACID DERIVATIVES | VANMOOR ARTHUR (US) | 1998-01-13 | — | — | US | disclosed |
| US-5626831-A | TREATMENT OF VIRUSES FOR UPPER RESPIRATORY INFECTIONS | VAN MOERKERKEN ARTHUR (US) | 1997-05-06 | — | — | US | disclosed |