Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647984 | 0.74 | CYP3A4 (0.34) | CYP3A4TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL8333134 | 0.74 | TSHR (0.30) | TSHR | |
| SCHEMBL10011526 | 0.73 | CYP3A4 (0.38) | CYP3A4TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL1357038 | 0.72 | — | — | |
| SCHEMBL8978426 | 0.72 | CYP3A4 (0.40) | CYP3A4TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL10869033 | 0.71 | ATM (0.37) | CYP3A4TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL10516 | 0.71 | — | — | |
| SCHEMBL2138838 | 0.71 | ADRB2 (0.43) | CYP3A4TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL9648981 | 0.71 | ADRB2 (0.43) | CYP3A4TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL10762136 | 0.71 | TSHR (0.44) | CYP3A4TSHRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780379-A | Process for the stereospecific polymerization of alpha-olefins and catalyst system which can be employed for this polymerization | SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) | 1998-07-14 | — | — | US | disclosed |
| EP-0149558-B1 | HIGH EFFICIENCY POLYMERIZATION CATALYST COMPONENT FOR USE IN THE POLYMERIZATION OF PROPYLENE AND HIGHER ALPHA-OLEFINS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4677088-A | COORDINATION CATALYST ORGANOALUMINUM COMPOUND AND LEWIS BASE | EXXON CHEMICAL PATENTS INC. (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0149558-A2 | High efficiency polymerization catalyst component for use in the polymerization of propylene and higher alpha-olefins | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| US-4525467-A | MIXED ALUMINUM HYDROCARBYL-LEWIS BASE COORDINATION CATALYST | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-06-25 | — | — | US | disclosed |