SCHEMBL8649378

SCHEMBL8649378

CC(C)[Si](OCCC1C=CCO1)(C(C)C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMYD2 Q9NRG4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20072253 0.74
SCHEMBL2533139 0.68 KDM4E (0.38)
SCHEMBL11673517 0.66
SCHEMBL3960213 0.66 SMYD2 (0.35) SMYD2
SCHEMBL5272661 0.66
SCHEMBL4631220 0.65
SCHEMBL8218055 0.64
SCHEMBL12216535 0.64
SCHEMBL19409928 0.63 ALDH1A1 (0.43)
SCHEMBL31163936 0.63 ALDH1A1 (0.44) SMYD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691964-B1 (3-KETOTETRAHYDROFURAN-2-YL)ETHANAL DERIVATIVES AND A METHOD FOR THEIR PREPARATION BIOCURE LTD (GB) 1998-09-02 EP disclosed
US-5684166-A MULTISTAGE REACTION OF TRANS-HEXEN-3-ENE-1,6-DIOL TO AN IODO ETHERIFICATION REACTION TO GIVE 3-IODOTETRAHYDROFURAN, PROTECTION OF HYDROXYL AND DISPLACEMENT OF IODINE FOR PRODUCT BIOCURE LIMITED (GB) 1997-11-04 US disclosed
EP-0691964-A1 (3-KETOTETRAHYDROFURAN-2-YL)ETHANAL DERIVATIVES AND A METHOD FOR THEIR PREPARATION BIOCURE LIMITED (GB) 1996-01-17 EP disclosed
WO-1994022849-A1 (3-KETOTETRAHYDROFURAN-2-YL)ETHANAL DERIVATIVES AND A METHOD FOR THEIR PREPARATION BIOCURE LIMITED (GB) 1994-10-13 WO disclosed