Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652565 | 0.89 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL8655156 | 0.88 | HCRTR2 (0.34) | HCRTR2HCRTR1 | |
| SCHEMBL8651738 | 0.88 | POLB (0.31) | — | |
| SCHEMBL8649547 | 0.86 | SCN9A (0.31) | SCN9A | |
| SCHEMBL8652846 | 0.86 | NPY2R (0.33) | HCRTR2HCRTR1 | |
| SCHEMBL8665513 | 0.86 | HCRTR1 (0.33) | HCRTR2HCRTR1 | |
| SCHEMBL8343961 | 0.86 | HCRTR2 (0.34) | HCRTR2 | |
| SCHEMBL8654149 | 0.86 | — | — | |
| SCHEMBL8655496 | 0.86 | POLB (0.33) | HCRTR2HCRTR1 | |
| SCHEMBL8655163 | 0.85 | POLB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |