Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 10/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668056 | 0.91 | KDM2B (0.34) | POLB | |
| SCHEMBL8651738 | 0.90 | POLB (0.31) | POLB | |
| SCHEMBL8655496 | 0.89 | POLB (0.33) | HCRTR1HCRTR2POLB | |
| SCHEMBL8652846 | 0.89 | NPY2R (0.33) | HCRTR1HCRTR2POLB | |
| SCHEMBL8343961 | 0.87 | HCRTR2 (0.34) | HCRTR2POLB | |
| SCHEMBL8652565 | 0.86 | FFAR4 (0.32) | — | |
| SCHEMBL8649950 | 0.86 | HCRTR2 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL8649547 | 0.86 | SCN9A (0.31) | POLB | |
| SCHEMBL8655156 | 0.86 | HCRTR2 (0.34) | HCRTR1HCRTR2POLB | |
| SCHEMBL8655163 | 0.85 | POLB (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | claimed |