Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10339529 | 0.98 | MAPT (0.45) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL9330992 | 0.87 | TSHR (0.53) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL8674955 | 0.86 | CA12 (0.65) | PDCD1CD274CA1CA2CA12 | |
| SCHEMBL27592818 | 0.84 | ALDH1A1 (0.48) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL9816876 | 0.81 | CA12 (0.59) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL9389363 | 0.80 | CYP4A11 (0.46) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL175074 | 0.80 | TSHR (0.44) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL11323128 | 0.79 | ALDH1A1 (0.42) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL6228537 | 0.79 | CA1 (0.70) | MAPTPDCD1CD274CA1CA2 | |
| SCHEMBL9193031 | 0.79 | KMT2A (0.65) | CA1CA2KMT2ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2223541-A | — | — | None | — | — | JP | disclosed |
| EP-0862578-A1 | ACTINOMYCIN D ANALOGUES | Phytera Symbion ApS (DK) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997010263-A1 | ACTINOMYCIN D ANALOGUES | AUDA PHARMACEUTICALS APS (DK) | 1997-03-20 | — | — | WO | disclosed |
| JP-H02223541-A | OPTICALLY ACTIVE COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING SAME AND FERROELECTRIC LIQUID CRYSTAL ELEMENT USING SAME | SHARP CORP | 1990-09-05 | — | — | JP | disclosed |