Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448036 | 0.88 | PPARA (0.52) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL31725947 | 0.87 | PTPN1 (0.48) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL1748990 | 0.84 | ACE (0.53) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL1748989 | 0.84 | ACE (0.53) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL7859251 | 0.83 | ACE (0.52) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL7859254 | 0.83 | ACE (0.52) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL5153113 | 0.83 | ACE (0.52) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL12737917 | 0.82 | PPARA (0.51) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL2796961 | 0.82 | PPARA (0.51) | PTPN1ITGB3ITGA2BSCN9AACE | |
| SCHEMBL3188805 | 0.82 | ITGB3 (0.71) | PTPN1ITGB3ITGA2BACEPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714497-A | EXHIBIT AFFINITY FOR BIOLOGICAL RECEPTORS OF NEUROPEPTIDE Y | SANOFI (FR) | 1998-02-03 | — | — | US | disclosed |