Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373246 | 1.00 | TSHR (0.49) | TSHRFABP7FABP5FKBP1AALDH1A1 | |
| SCHEMBL9250708 | 0.87 | TSHR (0.47) | TSHRFKBP1A | |
| SCHEMBL12869913 | 0.80 | TSHR (0.47) | TSHRFABP7FABP5FKBP1AALDH1A1 | |
| SCHEMBL10744674 | 0.78 | CASP1 (0.44) | ALDH1A1 | |
| SCHEMBL13889276 | 0.78 | TSHR (0.56) | TSHRFABP7FABP5FKBP1AALDH1A1 | |
| SCHEMBL14605828 | 0.78 | TSHR (0.56) | TSHRFABP7FABP5FKBP1AALDH1A1 | |
| SCHEMBL14117906 | 0.78 | TSHR (0.56) | TSHRFABP7FABP5FKBP1AALDH1A1 | |
| SCHEMBL9169159 | 0.78 | TSHR (0.56) | TSHRFABP7FABP5FKBP1AALDH1A1 | |
| SCHEMBL2178522 | 0.78 | TSHR (0.56) | TSHRFABP7FABP5FKBP1AALDH1A1 | |
| SCHEMBL9733234 | 0.78 | TSHR (0.56) | TSHRFABP7FABP5FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670310-B1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0670310-A1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-09-06 | — | — | EP | disclosed |