Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650372 | 1.00 | SCN9A (0.52) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL1310039 | 0.88 | PTPN1 (0.53) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL16448036 | 0.88 | PPARA (0.52) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL28956926 | 0.87 | PTPN1 (0.54) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL24981983 | 0.87 | ACE (0.49) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL28989259 | 0.87 | ACE (0.49) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL16448238 | 0.87 | PTPN1 (0.55) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL3376442 | 0.84 | TACR1 (0.60) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL3376451 | 0.84 | TACR1 (0.60) | SCN9APPARAPPARGACEITGB3 | |
| SCHEMBL31407351 | 0.84 | TACR1 (0.60) | SCN9APPARAPPARGACEITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714497-A | EXHIBIT AFFINITY FOR BIOLOGICAL RECEPTORS OF NEUROPEPTIDE Y | SANOFI (FR) | 1998-02-03 | — | — | US | disclosed |