Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.44 |
| ▸ | RARG | P13631 | 10/20 | 0.44 |
| ▸ | RARA | P10276 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650401 | 0.84 | RARB (0.44) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL1361021 | 0.81 | MEN1 (0.58) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7929375 | 0.79 | RARB (0.51) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8646306 | 0.79 | RARA (0.44) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7929427 | 0.79 | RARB (0.50) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7927675 | 0.79 | RARB (0.50) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8459842 | 0.78 | KMT2A (0.41) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7690768 | 0.78 | RARA (0.37) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7926531 | 0.78 | RARB (0.46) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL2917266 | 0.77 | RARB (0.48) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705167-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-06 | — | — | US | disclosed |