SCHEMBL8650600

CC(C)(C)N(O)C(=O)C1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	SRD5A2	P31213	20/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8611619	0.86	SRD5A2 (1.00)	SRD5A2
SCHEMBL8611622	0.86	SRD5A2 (1.00)	SRD5A2
SCHEMBL8612687	0.85	SRD5A2 (1.00)	SRD5A2
SCHEMBL8612685	0.85	SRD5A2 (1.00)	SRD5A2
SCHEMBL12651156	0.85	SRD5A2 (0.80)	SRD5A2
SCHEMBL12606608	0.85	SRD5A2 (0.80)	SRD5A2
SCHEMBL9159638	0.85	SRD5A2 (0.80)	SRD5A2
SCHEMBL19544537	0.85	SRD5A2 (0.80)	SRD5A2
SCHEMBL19544512	0.84	SRD5A2 (0.79)	SRD5A2
SCHEMBL8528588	0.84	SRD5A2 (0.76)	SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5708001-A	TESTOSTERONE-5A-REDUCTASE INHIBITORS	GLAXO WELLCOME INC. (US)	1998-01-13	—	—	US	disclosed
EP-0674651-A1	SUBSTITUTED 6-AZAANDROSTENONES	GLAXO WELLCOME INC. (US)	1995-10-04	—	—	EP	disclosed
WO-1994014833-A2	SUBSTITUTED 6-AZAANDROSTENONES	GLAXO WELLCOME INC. (US)	1994-07-07	—	—	WO	disclosed