Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 17/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565281 | 0.84 | LTB4R (0.62) | LTB4RLTB4R2 | |
| SCHEMBL8565892 | 0.80 | LTB4R (0.63) | LTB4RLTB4R2NR1H4 | |
| SCHEMBL8651831 | 0.79 | NR1H4 (0.53) | LTB4RLTB4R2NR1H4 | |
| SCHEMBL8650952 | 0.79 | LTB4R (0.59) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8653477 | 0.79 | LTB4R (0.58) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8653050 | 0.79 | LTB4R (0.58) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8654385 | 0.77 | LTB4R (0.74) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL9417857 | 0.77 | NR1H4 (0.60) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8653689 | 0.77 | NR1H4 (0.44) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8566927 | 0.77 | LTB4R (0.62) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579412-B1 | 1,2,4-trioxygenated benzene derivatives useful as a leukotriene antagonists | LILLY CO ELI (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5352690-A | For asthma, allergies | ELI LILLY AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0579412-A1 | 1,2,4-trioxygenated benzene derivatives useful as a leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |