Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.35 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654440 | 1.00 | KDM1A (0.46) | KDM1ALTA4HMAOANPY5RFFAR1 | |
| SCHEMBL7330311 | 1.00 | KDM1A (0.46) | KDM1ALTA4HMAOANPY5RFFAR1 | |
| SCHEMBL8653729 | 0.91 | KDM1A (0.38) | KDM1ALTA4HMAOAHTR6 | |
| SCHEMBL7337058 | 0.91 | KDM1A (0.38) | KDM1ALTA4HMAOAHTR6 | |
| SCHEMBL7334192 | 0.91 | KDM1A (0.38) | KDM1ALTA4HMAOAHTR6 | |
| SCHEMBL7337400 | 0.86 | SMPD1 (0.43) | KDM1ALTA4HMAOANPY5RSIGMAR1 | |
| SCHEMBL8652839 | 0.86 | SMPD1 (0.43) | KDM1ALTA4HMAOANPY5RSIGMAR1 | |
| SCHEMBL7337404 | 0.86 | SMPD1 (0.43) | KDM1ALTA4HMAOANPY5RSIGMAR1 | |
| SCHEMBL7331139 | 0.85 | MAOB (0.47) | LTA4HMAOA | |
| Hydrochloric Acid SCHEMBL8653992 | 0.85 | KDM1A (0.47) | KDM1AHTR6SIGMAR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | claimed |
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | disclosed |