Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653729 | 1.00 | KDM1A (0.38) | KDM1AMAOAMAOBLTA4HEPHX2 | |
| SCHEMBL7337058 | 1.00 | KDM1A (0.38) | KDM1AMAOAMAOBLTA4HEPHX2 | |
| SCHEMBL8654440 | 0.91 | KDM1A (0.46) | KDM1AMAOALTA4HHTR6 | |
| SCHEMBL7330311 | 0.91 | KDM1A (0.46) | KDM1AMAOALTA4HHTR6 | |
| SCHEMBL8650740 | 0.91 | KDM1A (0.46) | KDM1AMAOALTA4HHTR6 | |
| Maleic Acid SCHEMBL8650435 | 0.90 | LTA4H (0.38) | KDM1AMAOAMAOBLTA4HEPHX2 | |
| Fumaric Acid SCHEMBL8650441 | 0.90 | LTA4H (0.38) | KDM1AMAOAMAOBLTA4HEPHX2 | |
| Fumaric Acid SCHEMBL8650442 | 0.90 | LTA4H (0.38) | KDM1AMAOAMAOBLTA4HEPHX2 | |
| Maleic Acid SCHEMBL7337873 | 0.90 | LTA4H (0.38) | KDM1AMAOAMAOBLTA4HEPHX2 | |
| Maleic Acid SCHEMBL8650437 | 0.90 | LTA4H (0.38) | KDM1AMAOAMAOBLTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | claimed |
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | claimed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | claimed |
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | disclosed |