Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655496 | 0.90 | POLB (0.33) | POLB | |
| SCHEMBL8655163 | 0.88 | POLB (0.32) | POLB | |
| SCHEMBL8652002 | 0.88 | CRHR1 (0.34) | POLBCRHR1 | |
| SCHEMBL8668056 | 0.88 | KDM2B (0.34) | POLB | |
| SCHEMBL8651738 | 0.87 | POLB (0.31) | POLB | |
| SCHEMBL8652576 | 0.86 | POLB (0.30) | POLB | |
| SCHEMBL8652687 | 0.86 | POLB (0.30) | POLB | |
| SCHEMBL8652846 | 0.86 | NPY2R (0.33) | POLB | |
| SCHEMBL8655141 | 0.86 | POLB (0.31) | POLB | |
| SCHEMBL8343961 | 0.86 | HCRTR2 (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |