Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907284 | 0.91 | RECQL (0.41) | P2RX7RECQLMEN1KMT2A | |
| SCHEMBL8654379 | 0.89 | P2RX7 (0.39) | P2RX7NPC1RAB9AEPHX2 | |
| SCHEMBL8905990 | 0.89 | P2RX7 (0.37) | P2RX7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6480022 | 0.89 | P2RX7 (0.42) | P2RX7RECQLMEN1KMT2A | |
| SCHEMBL8652037 | 0.88 | P2RX7 (0.38) | P2RX7NPC1RAB9ARECQLANO1 | |
| SCHEMBL8653874 | 0.87 | P2RX7 (0.36) | P2RX7NPC1RAB9AEPHX2 | |
| SCHEMBL8655537 | 0.85 | P2RX7 (0.40) | P2RX7ANO1 | |
| SCHEMBL8652458 | 0.85 | P2RX7 (0.38) | P2RX7NPC1RAB9ARECQLANO1 | |
| SCHEMBL8657143 | 0.84 | P2RX7 (0.37) | P2RX7NPC1RAB9ARECQLKMT2A | |
| SCHEMBL8650622 | 0.84 | P2RX7 (0.37) | P2RX7NPC1RAB9ARECQLANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |