Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.83 |
| ▸ | MMP3 | P08254 | 9/20 | 0.83 |
| ▸ | MMP1 | P03956 | 2/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | MMP14 | P50281 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668760 | 0.89 | MMP2 (0.82) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8649701 | 0.87 | MMP2 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7427611 | 0.80 | MMP2 (0.54) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL29389301 | 0.80 | MMP2 (0.80) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8665571 | 0.79 | MMP2 (0.80) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8652786 | 0.78 | MMP2 (0.64) | MMP2MMP3 | |
| SCHEMBL16148632 | 0.78 | MMP2 (0.52) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL16148630 | 0.78 | MMP2 (0.52) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8650550 | 0.77 | MMP2 (0.62) | MMP2MMP3 | |
| SCHEMBL6413235 | 0.77 | MMP2 (0.65) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712390-B1 | SUCCINAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS GELATINASE AND COLLAGENASE INHIBITORS | CELLTECH THERAPEUTICS LTD (GB) | 1998-12-09 | — | — | EP | disclosed |
| US-5827890-A | ANGIOGENESIS INHIBITORS | CELLTECH THERAPEUTICS LTD. (GB) | 1998-10-27 | — | — | US | disclosed |
| WO-1995004033-A1 | SUCCINAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS GELATINASE AND COLLAGENASE INHIBITORS | CELLTECH LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |