Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652469 | 0.95 | HPGD (0.39) | HPGDSMN1; SMN2PTGS1PTGS2OPRM1 | |
| SCHEMBL21652471 | 0.94 | HPGD (0.41) | HPGDSMN1; SMN2PTGS1PTGS2OPRM1 | |
| SCHEMBL8651451 | 0.93 | OPRM1 (0.37) | SMN1; SMN2OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL21652465 | 0.92 | CA1 (0.38) | HPGDSMN1; SMN2PTGS1PTGS2OPRM1 | |
| SCHEMBL21652486 | 0.92 | CA1 (0.38) | HPGDSMN1; SMN2PTGS1PTGS2OPRM1 | |
| SCHEMBL21652485 | 0.90 | OPRM1 (0.36) | HPGDSMN1; SMN2PTGS1PTGS2OPRM1 | |
| SCHEMBL24024215 | 0.90 | OPRM1 (0.37) | HPGDSMN1; SMN2PTGS1PTGS2OPRM1 | |
| SCHEMBL21652472 | 0.88 | CA1 (0.39) | SMN1; SMN2OPRM1OPRD1OPRK1KMT2A | |
| SCHEMBL21652477 | 0.88 | OPRM1 (0.36) | HPGDSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL21652476 | 0.88 | OPRM1 (0.36) | HPGDSMN1; SMN2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |