Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651905 | 1.00 | SRD5A1 (0.54) | SRD5A1SRD5A2SHBG | |
| SCHEMBL9486929 | 0.86 | SRD5A1 (0.64) | SRD5A1SRD5A2SHBG | |
| SCHEMBL7909909 | 0.86 | SRD5A1 (0.64) | SRD5A1SRD5A2SHBG | |
| SCHEMBL7909915 | 0.86 | SRD5A1 (0.64) | SRD5A1SRD5A2SHBG | |
| SCHEMBL8651878 | 0.84 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8650014 | 0.84 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8650013 | 0.84 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8651218 | 0.80 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8651221 | 0.80 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8722381 | 0.79 | SRD5A1 (0.61) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700291-B1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1998-09-16 | — | — | EP | claimed |
| EP-0700291-B1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0700291-A4 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0700291-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO. INC. (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5359071-A | Selective antagonist of testosterone 5-alpha-reductase 1 | MERCK & CO., INC. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994020104-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO, INC. (US) | 1994-09-15 | — | — | WO | disclosed |