Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654389 | 1.00 | MAPT (0.41) | MAPTALDH1A1L3MBTL1ALPLCYP3A4 | |
| SCHEMBL8652690 | 1.00 | MAPT (0.41) | MAPTALDH1A1L3MBTL1ALPLCYP3A4 | |
| SCHEMBL8654662 | 0.99 | MAPT (0.39) | MAPTALDH1A1L3MBTL1ALPLCYP3A4 | |
| SCHEMBL6475365 | 0.88 | MEN1 (0.43) | MAPTALDH1A1L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL6481332 | 0.88 | MEN1 (0.43) | MAPTALDH1A1L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL6483593 | 0.88 | MEN1 (0.43) | MAPTALDH1A1L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL6475580 | 0.87 | MEN1 (0.41) | MAPTNPSR1 | |
| SCHEMBL8654879 | 0.86 | PYGL (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19ADRB2 | |
| SCHEMBL8657354 | 0.86 | PYGL (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19ADRB2 | |
| SCHEMBL8663533 | 0.86 | PYGL (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |