Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652585 | 0.92 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL8654863 | 0.88 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8652712 | 0.86 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL8651505 | 0.86 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL8658425 | 0.86 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL8655533 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1 | |
| Sc-57666 SCHEMBL213008 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8655028 | 0.83 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL8651836 | 0.82 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8652095 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724566-B1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 1998-10-07 | — | — | EP | claimed |
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | claimed |
| EP-0724566-B1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5663180-A | ANTIARTHRITIC, ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5420287-A | 1,2 diarylcyclopentenyl compounds for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5344991-A | Sulfonyl or sulfamyl derivatives for treatment of arthritis and pain | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |