Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107371 | 0.91 | POLB (0.82) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23521940 | 0.89 | CYP1A1 (0.70) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8585476 | 0.84 | HDAC4 (0.70) | — | |
| SCHEMBL3152473 | 0.84 | CYP1A1 (0.79) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3806017 | 0.83 | MEN1 (0.73) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1669619 | 0.82 | ALDH1A1 (0.70) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7109810 | 0.82 | POLB (0.70) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22773558 | 0.82 | POLB (0.70) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21788779 | 0.82 | POLB (0.70) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL24040103 | 0.82 | POLB (0.70) | POLBALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807688-A | ANTIBODY DIRECTED ANZYME PRODRUG THERAPY | ZENECA LIMITED (GB) | 1998-09-15 | — | — | US | disclosed |