Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654253 | 1.00 | HTR2A (0.38) | HTR2ATDP1FFAR1PARP15PARP10 | |
| SCHEMBL8653237 | 0.86 | HTR2A (0.48) | HTR2AKMT2A | |
| SCHEMBL7329303 | 0.86 | HTR2A (0.48) | HTR2AKMT2A | |
| SCHEMBL8652132 | 0.84 | POLB (0.44) | HTR2AMEN1KMT2AKDM4C | |
| SCHEMBL7365725 | 0.84 | MEN1 (0.48) | FFAR1MEN1KMT2AKDM4C | |
| SCHEMBL7328038 | 0.84 | MEN1 (0.48) | FFAR1MEN1KMT2AKDM4C | |
| SCHEMBL7333179 | 0.84 | MEN1 (0.48) | FFAR1MEN1KMT2AKDM4C | |
| SCHEMBL7335024 | 0.84 | POLB (0.44) | HTR2AMEN1KMT2AKDM4C | |
| SCHEMBL8653058 | 0.84 | HTR2A (0.40) | HTR2AFFAR1 | |
| SCHEMBL7329595 | 0.84 | HTR2A (0.40) | HTR2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |