Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | AHCY | P23526 | 5/20 | 0.47 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481897 | 0.82 | AHCY (0.57) | ADORA1AHCYADORA3ADORA2BHIF1A | |
| SCHEMBL1069001 | 0.81 | PRMT5 (0.55) | PRMT5WDR77ADORA1AHCYTRDMT1 | |
| SCHEMBL8433551 | 0.80 | ADORA1 (0.51) | ADORA1AHCYTRDMT1ADORA3ADORA2B | |
| SCHEMBL5580213 | 0.76 | ADORA1 (0.57) | PRMT5WDR77ADORA1AHCYTRDMT1 | |
| SCHEMBL8104254 | 0.75 | ADORA1 (0.55) | PRMT5WDR77ADORA1AHCYADORA3 | |
| SCHEMBL2107506 | 0.75 | ADORA1 (0.53) | PRMT5WDR77ADORA1AHCYTRDMT1 | |
| SCHEMBL2815316 | 0.75 | ADORA1 (0.49) | PRMT5WDR77ADORA1AHCYTRDMT1 | |
| SCHEMBL10381791 | 0.74 | ADORA1 (0.60) | PRMT5WDR77ADORA1AHCYADORA3 | |
| SCHEMBL8359104 | 0.74 | ADORA1 (0.75) | ADORA1TRDMT1TYMP | |
| SCHEMBL15993919 | 0.74 | ADORA1 (0.75) | ADORA1TRDMT1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747326-A | Isolated nucleic acid molecules which encode mammalian α2,8 polysialyl transferases | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1998-05-05 | — | — | US | disclosed |