SCHEMBL8652192

SCHEMBL8652192

O=C(O)c1ccc(Oc2ccc(-c3ccccc3)cc2)cc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.71
MCL1 Q07820 3/20 0.64
TDP1 Q9NUW8 3/20 0.64
GALK1 P51570 1/20 0.64
CASP6 P55212 1/20 0.64
PLEC Q15149 1/20 0.64
HNF4A P41235 2/20 0.53
ACMSD Q8TDX5 2/20 0.53
HPSE Q9Y251 1/20 0.52
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
PYGL P06737 2/20 0.49
PYGM P11217 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
FFAR1 O14842 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
APEX1 P27695 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278193 0.94 POLB (0.67) POLBMCL1TDP1GALK1CASP6
SCHEMBL29475149 0.94 POLB (0.67) POLBMCL1TDP1GALK1CASP6
SCHEMBL28480678 0.93 POLB (0.62) POLBMCL1TDP1GALK1CASP6
SCHEMBL30287662 0.91 POLB (0.77) POLBMCL1TDP1GALK1CASP6
SCHEMBL522949 0.91 POLB (0.77) POLBMCL1TDP1GALK1CASP6
SCHEMBL28576596 0.89 POLB (0.75) POLBMCL1TDP1GALK1CASP6
SCHEMBL30901880 0.89 POLB (0.73) POLBMCL1TDP1GALK1CASP6
SCHEMBL29406842 0.89 POLB (0.73) POLBMCL1TDP1GALK1CASP6
SCHEMBL30553345 0.89 POLB (0.73) POLBMCL1TDP1GALK1CASP6
SCHEMBL145176 0.89 POLB (0.73) POLBMCL1TDP1GALK1CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5821319-A COMPRISING STRUCTURAL UNITS DERIVED FROM PYROMELLITIC ANHYDRIDE, TEREPHTHALOYL CHLORIDE, 1,3-BIS/4-(4-AMINOPHENOXY)-ALPHA,ALPHA-DIMETHYLBENZYL/BENZENE MITSUI CHEMICALS, INC. (JP) 1998-10-13 US disclosed