Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864924 | 0.95 | DRD2 (0.43) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| SCHEMBL27355505 | 0.87 | DRD2 (0.41) | NPSR1TSHRDRD2DRD3CYP19A1 | |
| SCHEMBL27926693 | 0.72 | NPC1 (0.56) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| SCHEMBL28249044 | 0.72 | NPC1 (0.56) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| Cyanide SCHEMBL30330547 | 0.71 | NPC1 (0.51) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| Cyanide SCHEMBL30330308 | 0.71 | NPC1 (0.51) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| Cyanide SCHEMBL30330725 | 0.71 | NPC1 (0.51) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| SCHEMBL8645391 | 0.71 | CYP19A1 (0.34) | DRD2CYP19A1 | |
| SCHEMBL2186511 | 0.71 | — | — | |
| SCHEMBL28188544 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707003-B1 | Manufacture of 4-aryl-2-perfluoroalkyl-3-oxazolin-5-one from arylglycine | AMERICAN CYANAMID CO (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5574175-A | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | AMERICAN CYANAMID CO. (US) | 1996-11-12 | — | — | US | disclosed |
| CN-1133836-A | Process for manufacture of insecticidal arylpyrrolwa via oxazole amine intermediates | AMERICAN CYANAMID CO (US) | 1996-10-23 | — | — | CN | disclosed |
| EP-0713868-A1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | American Cyanamid Company (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0707003-A1 | Manufacture of 4-aryl-2-perfluoroalkyl-3-oxazolin-5-one from arylglycine | American Cyanamid Company (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5453508-A | Pesticide intermediate | AMERICAN CYANAMID COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| US-5446170-A | Reacting oxazole amine intermediate with halonitrile in presence of base | AMERICAN CYANAMID COMPANY (US) | 1995-08-29 | — | — | US | disclosed |