SCHEMBL8653137

SCHEMBL8653137

C[Si]1(C)C2=Cc3ccccc3C2[Zr](c2ccccc2)(c2ccccc2)C2C1=Cc1ccccc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5354270 0.81
SCHEMBL797252 0.79
SCHEMBL7774280 0.77 CYP11B1 (0.31)
SCHEMBL7766825 0.76
SCHEMBL9280881 0.72
SCHEMBL616008 0.72 KDM1A (0.34)
SCHEMBL797195 0.72 CYP11B1 (0.32)
SCHEMBL5087761 0.69 HTR1A (0.30)
SCHEMBL4442380 0.69
SCHEMBL7605520 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570126-B1 Method for producing graft-modified copolymers MITSUBISHI CHEM CORP (JP) 1998-09-30 EP disclosed
US-5334664-A Graft polymerization an unsaturated cyclic copolymer of propylene, bicycloheptene or tetracyclododecene with vinyl, vinylidene, unsaturated dicarboxylic acids or esters monomers MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1994-08-02 US disclosed
EP-0570126-A1 Method for producing graft-modified copolymers MITSUBISHI CHEMICAL CORPORATION (JP) 1993-11-18 EP disclosed