Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653385 | 0.86 | HRH1 (0.41) | HTR2AHRH1F2RL1 | |
| SCHEMBL8655785 | 0.82 | CYP19A1 (0.41) | CYP19A1HTR2AHRH1 | |
| SCHEMBL8655476 | 0.82 | SLC7A5 (0.45) | HTR2AHRH1 | |
| SCHEMBL6954666 | 0.79 | F2RL1 (0.43) | F2RL1 | |
| SCHEMBL954931 | 0.79 | F2RL1 (0.46) | CYP19A1F2RL1 | |
| SCHEMBL7762331 | 0.78 | HRH1 (0.42) | CYP19A1HTR2AHRH1 | |
| SCHEMBL2862310 | 0.78 | HRH1 (0.65) | CYP19A1HTR2AHRH1 | |
| SCHEMBL9659736 | 0.77 | HRH1 (0.55) | HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL7389223 | 0.76 | HRH1 (0.63) | CYP19A1HTR2AHRH1 | |
| SCHEMBL7908696 | 0.74 | CYP19A1 (0.42) | CYP19A1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| WO-1995029929-A1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS | ROUSSEL UCLAF (FR) | 1995-11-09 | — | — | WO | claimed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | claimed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | disclosed |
| WO-1995029929-A1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS | ROUSSEL UCLAF (FR) | 1995-11-09 | — | — | WO | disclosed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | disclosed |