Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655785 | 0.84 | CYP19A1 (0.41) | HTR2AHRH1KIF11MAOBAOC3 | |
| SCHEMBL8653269 | 0.82 | CYP19A1 (0.42) | HTR2AHRH1 | |
| SCHEMBL8653385 | 0.79 | HRH1 (0.41) | HTR2AHRH1 | |
| SCHEMBL2469476 | 0.78 | NPC1 (0.48) | SLC7A5NPC1RAB9AABL1TTBK1 | |
| SCHEMBL8653581 | 0.72 | AOC3 (0.40) | HTR2AHRH1FAAHMAOBAOC3 | |
| SCHEMBL7762331 | 0.72 | HRH1 (0.42) | HTR2AHRH1 | |
| SCHEMBL9659736 | 0.71 | HRH1 (0.55) | HTR2AHRH1 | |
| SCHEMBL2093778 | 0.70 | SLC7A5 (0.52) | SLC7A5KIF11SCN10AMAOBAOC3 | |
| SCHEMBL7908696 | 0.69 | CYP19A1 (0.42) | — | |
| SCHEMBL8654782 | 0.68 | ADRA2A (0.39) | HTR2AHRH1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | claimed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | disclosed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | disclosed |